3-phosphoglycerate kinase

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Phosphoglycerate kinase (PGK) is an enzyme that catalyzes the reversible transfer of a phosphate group from 1,3-bisphosphoglycerate (1,3-BPG) to ADP producing 3-phosphoglycerate (3-PG) and ATP. Like all kinases it is a transferase.

Chemical equation

 1,3BPG + ADP \rightleftharpoons 3PG + ATP


Rate equation

Random Bi-Bi reversible Michaelis-Menten euation for non-interacting substrates are used .


 \frac{V_{mf}\frac{[1,3BPG][ADP]}{K_{1,3BPG} K_{ADP}} - V_{mr}\frac{[3PG][ATP]}{K_{3PG} K_{ATP}}}{1 + \frac{[1,3BPG]}{K_{1,3BPG}} + \frac{[ADP]}{K_{ADP}} + \frac{[1,3BPG][ADP]}{K_{1,3BPG} K_{ADP}} + \frac{[3PG][ATP]}{K_{3PG} K_{ATP}} + \frac{[3PG]}{K_{3PG}} + \frac{[ADP]}{K_{ADP}} }

Parameter values

Alternative parameter values

Vrizlynn L.L. Thing, Tong-Wei Chua, Ming-Lee Cheong - Design of a Digital Forensics Evidence Reconstruction System for Complex and Obscure Fragmented File Carving
Computational Intelligence and Security, International Conference on 0:793-797, Los Alamitos, CA, USA,2011
Bibtex
Author : Vrizlynn L.L. Thing, Tong-Wei Chua, Ming-Lee Cheong
Title : Design of a Digital Forensics Evidence Reconstruction System for Complex and Obscure Fragmented File Carving
In : Computational Intelligence and Security, International Conference on -
Address : Los Alamitos, CA, USA
Date : 2011

Alvaro Mar\'in-Hern\'andez, Juan Carlos Gallardo-P\'erez, Sara Rodr\'iguez-Enr\'iquez, Rusely Encalada, Rafael Moreno-S\'anchez, Emma Saavedra - Modeling cancer glycolysis
Biochimica et Biophysica Acta (BBA) - Bioenergetics 1807(6):755 - 767, 11 2011
Bibtex
Author : Alvaro Mar\'in-Hern\'andez, Juan Carlos Gallardo-P\'erez, Sara Rodr\'iguez-Enr\'iquez, Rusely Encalada, Rafael Moreno-S\'anchez, Emma Saavedra
Title : Modeling cancer glycolysis
In : Biochimica et Biophysica Acta (BBA) - Bioenergetics -
Address :
Date : 11 2011