Serine out
This reaction describes the utilization of the endproduct Serine in other pathways.
Contents
Reaction equation
![Serine \leftrightarrow Serine_{out}](/wiki/images/math/9/7/4/9742bad9db24fd5dff081bf5b0de10be.png)
Rate equation
Simple reversible mass action rate law is used.
![v = K_{1} * [Serine] - K_{2} * [Serine_{out}]](/wiki/images/math/e/6/b/e6b7d292763cb679cbd1de648b4b0ddf.png)
Parameters
- For Transport reactions it is presumed to be at equilibrium, such that
and
.
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
![]() |
0.0103 [1] | ![]() |
Escherichia coli | |
![]() |
0.0103 | ![]() |
Parameters with uncertainty
- The transport rates have been modelled using mass action kinetics (i.e., as non-saturable, non-enzymatic reactions). No information is available about the uncertainty of these parameters. As these parameters are strictly positive, they are sampled using a log-normal distribution as are and values. The means of
are set to the value reported in Turnaev (2006) et al. [1] for the fixed-parameter model. The reaction is presumed to be at equilibrium, such that
and
. The sampling of the parameters are done in a way so that it ranges between
to allow a large exploration of the parameter space.
Parameter | Value | Organism | Remarks |
---|---|---|---|
![]() |
Sampled between 0.0000103 and 10.3 | HeLa cell line | |
![]() |
Sampled between 0.0000103 and 10.3 |