ATPase

From ISMOC
Revision as of 09:47, 8 May 2014 by Galib36 (talk | contribs) (Rate equation)
Jump to: navigation, search


ATPases catalyze the decomposition of ATP into ADP and a free phosphate ion. [1]

Chemical reaction

 ATP \rightarrow ADP + Pi

Rate equation

Mass action rate law is used in which K was the rate constant and ATP was the substrate concentration

v = K \times [ATP]

Parameter values

Parameter Value Organism Remarks
K 3 \times 10^{-3} [2] HeLa cell line

Parameters with uncertainty

  • Three value of K for ATPase has been reported in Hernandez (2011) et. al. [2]: 0.0042, 0.0045 for Normoxia and 0.003 for Hypoxia. Taking the average and calculating the Std. Dev. the value is 0.0039 \pm 0.00079
Parameter Value Organism Remarks
K 0.0039 \pm 0.00079 HeLa cell line

References

  1. Geider, K. and Hofmann-Berling, H. (1981). Proteins controlling the helical structure of DNA. Annu. Rev. Biochem. 50: 233–260.
  2. 2.0 2.1 Marín-Hernández A, Gallardo-Pérez JC, Rodríguez-Enríquez S et al (2011) Modeling cancer glycolysis. Biochim Biophys Acta 1807:755–767 (doi)