Phosphoserine phosphatase
This enzyme converts PSER to Serine.
Contents
Reaction equation
Rate equation
Special rate law is used. [1]
Parameters
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
0.25 [2] | mM | Escherichia coli | ||
1.43 [2] | 1/s | |||
0.0015[2] | mM | |||
0.15[2] | mM |
Parameters with uncertainty
- is the enzyme concentration and therefore considered to be constant.
- The value of is reported as for human brain in [3].
- Two values of for Porphyromonas gingivalis (nonmotile, Gram-negative, rod-shaped, anaerobic, pathogenic bacterium) are reported in Tribble et. al.[4]; 1.508, 2.94. The value with uncertainty comes as .
- For 10% uncertainty for the reported value is considered.
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
0.25 | mM | Escherichia coli | ||
1/s | Porphyromonas gingivalis | |||
[3] | mM | Human brain | ||
mM | Escherichia coli |
References
- ↑ Smallbone K, Stanford NJ (2013). Kinetic modeling of metabolic pathways: Application to serine biosynthesis. In: Systems Metabolic Engineering, Humana Press. pp. 113–121
- ↑ 2.0 2.1 2.2 2.3 Turnaev II, Ibragimova SS, Usuda Y et al (2006). Mathematical modeling of serine and glycine synthesis regulation in Escherichia coli. Proceedings of the fifth international conference on bioinformatics of genome regulation and structure 2:78–83 Cite error: Invalid
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tag; name "Turnaev_2006" defined multiple times with different content - ↑ 3.0 3.1 Shetty, V.; Shetty, K.T. (1990), Phosphoserine phosphatase of human brain: partial purification, characterization, regional distribution, and effect of certain modulators including psychoactive drugs, Neurochem. Res. 16, 1203-1210
- ↑ Tribble, G.D.; Mao, S.; James, C.E.; Lamont, R.J. (2006), A Porphyromonas gingivalis haloacid dehalogenase family phosphatase interacts with human phosphoproteins and is important for invasion, Proc. Natl. Acad. Sci. USA 103, 11027-11032 (2006)