Hexose-6-phosphate isomerase

The enzyme Hexose-6-phosphate isomerase converts glucose 6-phosphate into its isomer fructose 6-phosphate. Isomers have the same molecular formula, but the atoms of each molecule are arranged differently.

Chemical reaction

$Glc6P \rightleftharpoons Fru6P$

Rate equation

Reversible competitive inhibition with Ery4P, 6PG and FBP

$\frac{V_{mf}\frac{[Glc6P]}{K_{Glc6P}} - V_{mr} \frac{[Fru6P]}{K_{Fru6P}} }{ 1 + \frac{[Glc6P]}{K_{Glc6P}} + \frac{[Fru6P]}{K_{Fru6P}} + \frac{[ERY4P]}{K_{ERY4P}} + \frac{[6PG]}{K_{6PG}} + \frac{[FBP]}{K_{FBP}} }$