Glycogen phosphorylase
Glycogen phosphorylase (GP) is a dimeric enzyme that catalyses the reaction in which the terminal glucose residue from a glycogen chain is phosphorylated and cleaved from the chain, releasing it as Glc1P.
Chemical equation
Rate equation
MWC model was used to formualte the rate law. [1]
An alternative rate equation without considering the allosteric regulation is given as [2]
Parameter values
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
2 | Dimensionless | Recombinant, human muscle | ||
50 | ||||
2.08 | mM | |||
4.32 | mM | |||
41.53 | mM | |||
0.67 | mM | |||
82.02 | mM | |||
27.92 | mM | |||
mM | ||||
0.53 | mM | |||
3.9 | mM | |||
7.42 | mM | |||
0.56 | mM | |||
0.27 | mM | |||
5.93 | Dimensionless | |||
34741 | Dimensionless |
The parameter for the alternative equation are
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
50 | Rabbit | |||
Failed to parse (Cannot store math image on filesystem.): Ka | 4 | mM | ||
Failed to parse (Cannot store math image on filesystem.): Kb | 1.7 | mM | ||
Failed to parse (Cannot store math image on filesystem.): Kp | 2.7 | mM | ||
Failed to parse (Cannot store math image on filesystem.): Kq | 0.15 | mM | ||
Failed to parse (Cannot store math image on filesystem.): Ki_1 | 2 | mM | ||
Failed to parse (Cannot store math image on filesystem.): Ki_2 | 4.7 | mM | ||
Failed to parse (Cannot store math image on filesystem.): Ki_3 | 10.1 | mM | ||
0.42 | mM |