Difference between revisions of "Glucose Transporter"
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|Vm in U × (mg total cellular protein) | |Vm in U × (mg total cellular protein) | ||
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| − | |<math>K_{eq} | + | |<math>K_{eq}</math> |
|1 | |1 | ||
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Revision as of 13:02, 3 March 2014
Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose over a plasma membrane. Glucose is a vital source of energy for all life.
Contents
Chemical equation
Rate equation
Mono-Substrate reversible Michaelis-Menten with Haldane substitution is used[1].
![v = \frac{V_{mf}\Big([Glucose_{out}] - \frac{[Glucose_{in}]}{K_{eq}}\Big)}{K_{Glucose_{out}}\Big(1 + \frac{[Glucose_{in}]}{K_{Glucose_{in}}}\Big) + [Glucose_{out}}]](/wiki/images/math/a/b/b/abb0a304e70deb15ea4131439c9ee956.png)
Parameters
| Parameter | Value | Organism | Remarks |
|---|---|---|---|
|
0.055 [2] | Human Tumor Cell | Vm in U × (mg total cellular protein) |
|
1 | ||
| Failed to parse (syntax error): K_{Glucose_{in} | 10 | ||
| <math> | K_{Glucose_{out} | 9.3 | |
| Total | 15.00 |
Alternative parameter values
References
- ↑ Marín-Hernández A, Gallardo-Pérez JC, Rodríguez-Enríquez S et al (2011). Modeling cancer glycolysis. Biochim Biophys Acta, 1807:755–767 (doi)
- ↑ Rodríguez-Enríquez S, Marín-Hernández A, Gallardo-Pérez J C, et. al.(2009). Kinetics of transport and phosphorylation of glucose in cancer cells. Journal of Cell. Physiology, 221 , pp. 552–559 (doi)
