Difference between revisions of "Phosphoglycerate dehydrogenase"
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==Rate equation== | ==Rate equation== | ||
| − | Modified rate equation is used <ref name = "Smallbone_2013">Smallbone K, Stanford NJ (2013). ''Kinetic modeling of metabolic pathways: Application to serine biosynthesis. In: Systems Metabolic Engineering | + | Modified rate equation is used <ref name = "Smallbone_2013">Smallbone K, Stanford NJ (2013). ''Kinetic modeling of metabolic pathways: Application to serine biosynthesis''. In: Systems Metabolic Engineering, Humana Press. pp. 113–121</ref> |
<center><math> \frac{ serA*K_{cat}A.\frac{[3PG]}{Ka_{3PG}}}{\frac{1 + \frac{[3PG]}{Ka_{3PG}} + \frac{[PHP]}{Ka_{PHP}} }{1+ \frac{[SER]}{KiA_{SER}}}} </math></center> | <center><math> \frac{ serA*K_{cat}A.\frac{[3PG]}{Ka_{3PG}}}{\frac{1 + \frac{[3PG]}{Ka_{3PG}} + \frac{[PHP]}{Ka_{PHP}} }{1+ \frac{[SER]}{KiA_{SER}}}} </math></center> | ||
Revision as of 12:00, 3 March 2014
The enzyme Phosphoglycerate dehydrogenase (PDH) catalyzes the reaction to convert 3-phospho-D-glycerate (P3G) to phosphonooxypyruvate (PHP). The cofactors NADH and NAD+ are not considered in this reaction.
Chemical equation
Rate equation
Modified rate equation is used [1]
![\frac{ serA*K_{cat}A.\frac{[3PG]}{Ka_{3PG}}}{\frac{1 + \frac{[3PG]}{Ka_{3PG}} + \frac{[PHP]}{Ka_{PHP}} }{1+ \frac{[SER]}{KiA_{SER}}}}](/wiki/images/math/e/1/8/e1804c036835cc92c33f583f6c5c526d.png)
Parameters
References
- ↑ Smallbone K, Stanford NJ (2013). Kinetic modeling of metabolic pathways: Application to serine biosynthesis. In: Systems Metabolic Engineering, Humana Press. pp. 113–121
