Difference between revisions of "Enolase"
(Created page with "'''Enolase''', also known as phosphopyruvate hydratase, catalysis the conversion of [http://en.wikipedia.org/wiki/2-phosphoglycerate 2-phosphoglycerate] (2-PG) to [http://en.w...") |
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'''Enolase''', also known as phosphopyruvate hydratase, catalysis the conversion of [http://en.wikipedia.org/wiki/2-phosphoglycerate 2-phosphoglycerate] (2-PG) to [http://en.wikipedia.org/wiki/Phosphoenolpyruvate phosphoenolpyruvate] (PEP). This is the penultimate step of glycolysis. | '''Enolase''', also known as phosphopyruvate hydratase, catalysis the conversion of [http://en.wikipedia.org/wiki/2-phosphoglycerate 2-phosphoglycerate] (2-PG) to [http://en.wikipedia.org/wiki/Phosphoenolpyruvate phosphoenolpyruvate] (PEP). This is the penultimate step of glycolysis. | ||
| + | |||
| + | ==Chemical equation== | ||
| + | <center><math>2PG \rightleftharpoons PEP</math></center> | ||
| + | |||
| + | ==Rate equation== | ||
| + | Mono-substrate reversible Michaelis-Menten equation is used. <ref name="Hernandez2011"> Marín-Hernández A, Gallardo-Pérez JC, Rodríguez-Enríquez S et al (2011) Modeling cancer glycolysis. Biochim Biophys Acta 1807:755–767 ([http://dx.doi.org/10.1016/j.bbabio.2010.11.006 doi]) </ref> | ||
| + | <center><math> \frac{V_{mf}\frac{[2PG]}{K_{2PG}}-V_{mr}\frac{[PEP]}{K_{PEP}}}{1 + \frac{[2PG]}{K_{2PG}} + \frac{[PEP]}{K_{PEP}}} </math></center> | ||
| + | |||
| + | ==Parameter values== | ||
| + | ==Alternative parameter values== | ||
| + | |||
| + | ==References== | ||
| + | <references/> | ||
Revision as of 15:59, 27 February 2014
Enolase, also known as phosphopyruvate hydratase, catalysis the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP). This is the penultimate step of glycolysis.
Contents
Chemical equation
Rate equation
Mono-substrate reversible Michaelis-Menten equation is used. [1]
![\frac{V_{mf}\frac{[2PG]}{K_{2PG}}-V_{mr}\frac{[PEP]}{K_{PEP}}}{1 + \frac{[2PG]}{K_{2PG}} + \frac{[PEP]}{K_{PEP}}}](/wiki/images/math/6/a/9/6a9ca37a2fd76b4eb56a1e6a5cfb67d0.png)
