Difference between revisions of "Mitocondrial pyruvate metabolism"

Revision as of 10:13, 12 May 2014

Mitocondrial pyruvate metabolism(MPM) is an enzyme that generates ATP form pyruvate.

Pyruvate + 13ADP + 13Pi \rightarrow 13ATP

Chemical reactions proceed to equilibrium within closed systems. For a simple reaction $A \rightarrow B$ it is defined as $K_{eq} = \frac{[B]_{eq}}{[A]_{eq}}$ where forward and reverse rates are equal.

Constant flux is used where $v = 1 \times 10^{-4}$ is considered.

Parameter	Value	Organism	Remarks
$V$	$1 \times 10^{-4}$ ^[1]	HeLa cell line	Constant flux

↑ Marín-Hernández A, Gallardo-Pérez JC, Rodríguez-Enríquez S et al (2011) Modeling cancer glycolysis. Biochim Biophys Acta 1807:755–767 (doi)

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 ==Rate equation==
+*Chemical reactions proceed to equilibrium within closed systems. For a simple reaction <math>A \rightarrow B</math> it is defined as <math>K_{eq} = \frac{[B]_{eq}}{[A]_{eq}}</math> where forward and reverse rates are equal.
 Constant flux is used where <math> v = 1 \times 10^{-4}</math> is considered.
 ==Parameter values==