Difference between revisions of "Transketolase"

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'''Transketolase''' is an enzyme that catalyzes two important reactions in [http://en.wikipedia.org/wiki/Pentose_phosphate_pathway Pentose Phosphate Pathway].
 
'''Transketolase''' is an enzyme that catalyzes two important reactions in [http://en.wikipedia.org/wiki/Pentose_phosphate_pathway Pentose Phosphate Pathway].
  

Latest revision as of 10:54, 9 May 2014

Transketolase is an enzyme that catalyzes two important reactions in Pentose Phosphate Pathway.

Chemical reaction

 Ery4P + Xy5P \rightarrow Fru6P + Gly3P

Rate equation

Constant flux is used where  v = 9.50e^{-005} is considered.


Parameter values

Parameter Value Organism Remarks
V 9.5 \times 10^{-5} [1] HeLa cell line Constant flux

Parameters with uncertainty

  • In Hernandez (2011) et. al. the uncertainty in TK activity has been reported to be 10%. In our model we considered the same percentage of error for the TK flux value.
Parameter Value Organism Remarks
V 9.5 \times 10^{-5} \pm 9.5 \times 10^{-6} [1] HeLa cell line Constant flux

References

  1. 1.0 1.1 Marín-Hernández A, Gallardo-Pérez JC, Rodríguez-Enríquez S et al (2011) Modeling cancer glycolysis. Biochim Biophys Acta 1807:755–767 (doi)