Glucose Transporter

Glucose transporters are a wide group of membrane proteins that facilitate the transport of glucose over a plasma membrane. Glucose is a vital source of energy for all life.

Chemical equation

$Glucose_{out} \rightleftharpoons Glucose_{in}$

Rate equation

Mono-Substrate reversible Michaelis-Menten with Haldane substitution is used.

$v = \frac{V_{mf}\Big([Glucose_{out}] - \frac{[Glucose_{in}]}{K_{eq}}\Big)}{K_{Glucose_{out}}\Big(1 + \frac{[Glucose_{in}]}{K_{Glucose_{in}}}\Big) + [Glucose_{out}]}$

Parameter values

Parameter	Value	Units	Organism	Remarks
$V_{mf}$	.017	$\text{mM min}^{-1}$	HeLa cell line	Vm is converted to $\text{mM min}^{-1}$ from U × (mg total cellular protein) at $37^{\circ}$C
$K_{eq}$	1
$K_{Glucose_{in}}$	9.3	mM
$K_{Glucose_{out}}$	10	mM