Difference between revisions of "Glycogen phosphorylase"
(→Rate equation) |
(→Parameter values) |
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! Remarks | ! Remarks | ||
|- | |- | ||
− | |<math>V_{ | + | |<math>V_{maxf}</math> |
|50 | |50 | ||
|<math>\text{mM min}^{-1}</math> | |<math>\text{mM min}^{-1}</math> | ||
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|rowspan="9"| | |rowspan="9"| | ||
|- | |- | ||
− | |<math> | + | |<math>K_{iGlyf}</math> |
− | | | + | |15 |
|mM | |mM | ||
|- | |- | ||
− | |<math> | + | |<math>K_{Pi}</math> |
− | | | + | |4 |
|mM | |mM | ||
|- | |- | ||
− | |<math> | + | |<math>K_{Glyb}</math> |
− | | | + | |0.15 |
|mM | |mM | ||
|- | |- | ||
− | |<math> | + | |<math>K_{iGlc1P}</math> |
− | | | + | |10.1 |
|mM | |mM | ||
|- | |- | ||
− | |<math> | + | |<math>K_{iPi}</math> |
− | | | + | |4.6 |
|mM | |mM | ||
|- | |- | ||
− | |<math> | + | |<math>K_{iGlyb}</math> |
− | |4. | + | |4.4 |
|mM | |mM | ||
|- | |- | ||
− | |<math> | + | |<math>K_{Glyf}</math> |
− | | | + | |1.7 |
|mM | |mM | ||
|- | |- |
Revision as of 12:03, 1 April 2014
Glycogen phosphorylase (GP) is a dimeric enzyme that catalyses the reaction in which the terminal glucose residue from a glycogen chain is phosphorylated and cleaved from the chain, releasing it as Glc1P.
Chemical equation
Rate equation
MWC model was used to formualte the rate law. [1]
An alternative rate equation without considering the allosteric regulation is given as [2]
Parameter values
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
2 | Dimensionless | Recombinant, human muscle | ||
50 | ||||
2.08 | mM | |||
4.32 | mM | |||
41.53 | mM | |||
0.67 | mM | |||
82.02 | mM | |||
27.92 | mM | |||
mM | ||||
0.53 | mM | |||
3.9 | mM | |||
7.42 | mM | |||
0.56 | mM | |||
0.27 | mM | |||
5.93 | Dimensionless | |||
34741 | Dimensionless |
The parameter for the alternative equation are
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
50 | Rabbit | |||
15 | mM | |||
4 | mM | |||
0.15 | mM | |||
10.1 | mM | |||
4.6 | mM | |||
4.4 | mM | |||
1.7 | mM | |||
0.42 | mM |