Difference between revisions of "3-phosphoglycerate mutase"
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|<math>V_{mf}</math> | |<math>V_{mf}</math> | ||
− | | | + | |0.94 <ref name="Hernandez_2006"> Marín-Hernández A , Rodríguez-Enríquez S, Vital-González P A, ''et al.'' (2006). ''Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase''. FEBS J., 273 , pp. 1975–1988([http://dx.doi.org/doi:10.1111/j.1742-4658.2006.05214.x doi]) </ref> |
| <math> \text{mM min}^{-1} </math> | | <math> \text{mM min}^{-1} </math> | ||
|rowspan="4"|HeLa cell line | |rowspan="4"|HeLa cell line | ||
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|<math>V_{mr}</math> | |<math>V_{mr}</math> | ||
− | | | + | |0.36 <ref name="Hernandez_2006"></ref> |
|<math> \text{mM min}^{-1} </math> | |<math> \text{mM min}^{-1} </math> | ||
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Revision as of 16:42, 28 March 2014
Phosphoglycerate mutase (PGAM) is an enzyme that catalyzes the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG).
Contents
Chemical equation
Rate equation
Mono-substrate reversible Michaelis-Menten equation is used. [1]
Parameter values
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
0.94 [2] | HeLa cell line | |||
0.36 [2] | ||||
0.19[1] | mM | |||
0.12[1] | mM |
Alternative parameter values
References
- ↑ 1.0 1.1 1.2 Marín-Hernández A, Gallardo-Pérez JC, Rodríguez-Enríquez S et al (2011) Modeling cancer glycolysis. Biochim Biophys Acta 1807:755–767 (doi)
- ↑ 2.0 2.1 Marín-Hernández A , Rodríguez-Enríquez S, Vital-González P A, et al. (2006). Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase. FEBS J., 273 , pp. 1975–1988(doi)