Difference between revisions of "Pyrophosphate phosphohydrolase"
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==Chemical equation== | ==Chemical equation== | ||
− | <center><math> | + | <center><math>PPi \rightarrow 2 Pi</math></center> |
==Rate equation== | ==Rate equation== | ||
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|rowspan="1"| | |rowspan="1"| | ||
|- | |- | ||
− | |<math>K_{m}^{ | + | |<math>K_{m}^{PPi}</math> |
|<math>0.96 </math> | |<math>0.96 </math> | ||
|mM | |mM | ||
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==Parameters with uncertainty== | ==Parameters with uncertainty== | ||
− | * The maximum | + | * The minimum and maximum value for <math>K_{m}^{PPi}</math> has been reported to be 0.25 and 1.67. Calculating the mean and Std. Dev. using the '''range formula''' gives a value of <math>0.96 \pm 0.35</math> for this parameter. |
+ | * No Std. Dev. for <math>V_{max}</math> have been reported. Therefore the relative percent standard error is calculated for all the <math>V_{max}</math> which is <math>\approx 71%</math>. Taking this value the Std. Dev. for <math>V_{max}</math> is 0.2556. | ||
{|class="wikitable" | {|class="wikitable" | ||
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|- | |- | ||
|<math>V_{max}</math> | |<math>V_{max}</math> | ||
− | |<math>0.36</math> | + | |<math>0.36 \pm 0.2556</math> |
|<math>mM/min^{-1}</math> | |<math>mM/min^{-1}</math> | ||
|Human Liver | |Human Liver | ||
|rowspan="1"| | |rowspan="1"| | ||
|- | |- | ||
− | |<math>K_{m}^{ | + | |<math>K_{m}^{PPi}</math> |
|<math>0.96 \pm 0.35</math> | |<math>0.96 \pm 0.35</math> | ||
|mM | |mM |
Latest revision as of 13:18, 1 July 2014
Pyrophosphate phosphohydrolase that catalyze the reaction that converts Pyrophosphate into two molecules of Phosphate.
Contents
Chemical equation
Rate equation
Simple Michaelis-Menten rate law is used for this reaction [1]
Parameter values
- A mean body weight is defined as 75Kg in Konig et. al [1]. The is calculated by multiplying the reported value with body weight.
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
Human Liver | ||||
mM | Human cancer |
Parameters with uncertainty
- The minimum and maximum value for has been reported to be 0.25 and 1.67. Calculating the mean and Std. Dev. using the range formula gives a value of for this parameter.
- No Std. Dev. for have been reported. Therefore the relative percent standard error is calculated for all the which is . Taking this value the Std. Dev. for is 0.2556.
Parameter | Value | Units | Organism | Remarks |
---|---|---|---|---|
Human Liver | ||||
mM | Rat liver |