| Abbreviation |
Name
|
| [E]0 |
Enzyme concentration
|
| 15-PGDH |
15 hydroxy prostaglandin dehydrogenase
|
| 46BR.1N |
46BR dermal fibroblasts
|
| 5-HEDH |
5-hydroxyeicosanoid dehydrogenase
|
| AA |
Arachidonic acid
|
| ABC |
ATP-binding cassette transporters
|
| ABC_CI |
ATP-binding cassette transporter competitive inhibition term
|
| ACS |
American chemical society
|
| AKR13 |
Aldo-keto reductase family 1 member C3
|
| ATP |
Adenosine 5′-triphosphate
|
| BCA |
Bicinchoninic acid
|
| BHT |
2, 6-ditert-butyl-4-methylphenol
|
| BSA |
Bovine serum albumin
|
| COX |
Cyclooxygenase
|
| cPGES |
Cytosolic Prostaglandin E Synthase
|
| CYP P450 |
Cytochrome P450
|
| DC |
Dendritic cells
|
| DCM |
Dichloromethane
|
| DGLA |
Cis-8,11,14-eicosatrienoic acid
|
| DHA |
Cis-4,7,10,13,16,19-docosahexaenoic acid
|
| DMEM |
Dulbecco’s modified eagle medium
|
| DMSO |
Dimethyl sulfoxide
|
| DT |
Doubling time
|
| DTT |
Dithiothreitol
|
| EC |
Endothelial cell
|
| EDTA |
Ethylenediaminetetraacetic acid
|
| EPA |
Cis-5,8,11,14,17-Eicosapentaenoic acid
|
| ER |
Endoplasmic reticulum
|
| ESI |
Electrospray ionisation
|
| FAME |
Fatty acids methyl esters
|
| FBS |
Foetal bovine serum
|
| FID |
Flame ionisation detector
|
| FLAP |
Arachidonate 5-lipoxygenase-activating protein
|
| GC |
Gas chromatography
|
| GCV |
Geometric coefficient of variation
|
| HaCaT |
Human adult low-calcium high-temperature keratinocyte
|
| HETE |
Hydroxy-eicosatetraenoic acid
|
| HL |
Half-life
|
| HPETE |
Hydroperoxy-eicosatetraenoic acid
|
| H-PGDS |
Hemopoietic PGDS
|
| HPLC |
High performance liquid chromatography
|
| IQR |
Inter quartile range
|
| IS |
Internal standard
|
| kcat |
Enzyme turnover number
|
| KDO2-lipid A |
Di[3-deoxy-D-manno-octulosonyl]-lipid A
|
| Keq |
Equilibrium constant
|
| Kf |
Forward reaction rate constant
|
| Ki |
Inhibitor constant
|
| KD |
Dissociation constant of the enzyme-substrate complex
|
| Kmp |
Michaelis constant for the product
|
| Kms |
Michaelis constant for the substrate
|
| Kr |
Reverse reaction rate constant
|
| KS test |
Kolmogorov–Smirnov test
|
| LC |
Liquid chromatography
|
| LDL |
Low density lipid
|
| LL |
Log likelihood function
|
| LOX |
Lipoxygenase
|
| L-PGDS |
Lipocalin PGDS
|
| LT |
Leukotriene
|
| LTA4H |
Leukotriene A4 hydrolase
|
| LTC4S |
Leukotriene C4 synthase
|
| MAA |
Membrane arachidonic acid
|
| MALDI-TOF |
Matrix assisted laser desorption ionization-time of flight
|
| MEME |
Minimum essential medium eagle
|
| mPGES |
Microsomal PGES
|
| MRM |
Multiple reaction monitoring
|
| MS |
Mass spectrometry
|
| MTOI |
Multiple target optimal intervention
|
| MTT |
3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide
|
| n-3 PUFA |
Omega-3 polyunsaturated fatty acid
|
| n-6 PUFA |
Omega-6 polyunsaturated fatty acid
|
| NAD/NADH |
Nicotinamide adenine dinucleotide
|
| NADP/NADPH |
Nicotinamide adenine dinucleotide phosphate
|
| NSAID |
Nonsteroidal anti-inflammatory drug
|
| ODEs |
Ordinary differential equations
|
| OxoETE |
Oxo-eicosatetraenoic acid
|
| P |
Product
|
| PAF |
Platelet-activating factor
|
| PBS |
Dulbecco’s phosphate buffered saline
|
| PC |
Phosphatidylcholine
|
| PDEs |
Partial differential equations
|
| PE |
Phosphatidylethanolamine
|
| PG |
Prostaglandin
|
| PGDS |
Prostaglandin D synthase
|
| PGES |
Prostaglandin E synthase
|
| PGFS |
Prostaglandin F synthase
|
| PGIS |
Prostaglandin I synthase
|
| PGT |
Prostaglandin transporter
|
| PGT_CI |
Prostaglandin transporter competitive inhibition term
|
| PHGPx |
Phospholipid hydroperoxide glutathione peroxidase
|
| PKU |
Phenylketonuria
|
| PLA2 |
Phospholipase A2 enzyme
|
| PLT |
Platelet cell
|
| PMN |
Human polymorphonuclear leukocyte
|
| PPARϒ |
Peroxisome proliferator-activated receptor γ
|
| PTGR-2 |
Prostaglandin reductase 2
|
| PTGR-2 |
Prostaglandin reductase 2
|
| PUFA |
Polyunsaturated fatty acids
|
| Q |
Quadrupole
|
| R |
Gas constant
|
| S |
Substrates
|
| SPE |
Solid-phase extraction
|
| SRM |
Selected reaction monitoring
|
| SWATH-MS |
Sequential window acquisition of all theoretical mass spectra
|
| Th2 |
T helper type 2 cell
|
| TP |
TP receptor
|
| TX |
Thromboxane
|
| TXAS |
Thromboxane A synthase
|
| UPLC |
Ultrahigh performance liquid chromatography
|
| UV |
Ultraviolet
|
| UVR |
Ultraviolet radiation
|
| Vmax |
Maximal rate
|
